It's early autumn and Dr. Headley eagerly demonstrates what seems to be a miraculous cure for tuberculosis. Not far from where he is working, the disease seems preparing to soon claim yet another life, a teenage girl named Winifred. Winifred's mother and little sister Trixie are devastated. When Trixie hears the family doctor say of Winifred that "when the last leaf falls, she will have passed away," she interprets the doctor's words literally. Thinking over what she has heard, she determines to do everything possible to save her sister.

An aristocrat's daughter falls in love with a visiting archaeologist, but he holds a secret that could drive them apart.

A couple, cheated by a vile businessman, kidnap his wife in retaliation, without knowing that their enemy is delighted they did.

An Easter Parable: As lingering pneumonia takes her will to live, a young girl decides that she will die when the last leaf drops from a dying vine outside her window. Her neighbor, an elderly artist frustrated by his inability to paint what is in his heart, follows the example of the Savior and makes the ultimate sacrifice to save her life. In doing so, he creates the masterpiece he has been struggling to paint.

The Pink Panther employs various strategies in an effort to get himself a big holiday dinner.

Two bandits learn that kidnapping is a very profitable business. So they decide to kidnap local rich person's son in hope to get a substantial ransom.

In Paris, scoundrel mates Paolo and Antoine Venturen hope to get rich quick by asking ransom fro rich Mr. Jumelin's preteen son Eric. Masquerading as Indians, the scamp's favorite game, does the trick. They soon learn such bratty rascal is more trouble then he's worth. The boy's a P.I. instead of paying, and it gets worse.

John Steinbeck introduces a quintet of five of O. Henry's most celebrated stories from his New York Period (1902-1910) in this anthology film.

In basis of film are facts from biography of the American writer O. Henry and two his short stories.

Sergeant sets out to capture an infamous outlaw called The Cisco Kid.

A kidnapped boy proves to be more than his abductor can handle.

In a building site, a worker agonizes, after an accident, and tells his son about the virtues of honest work, but he's not heard. Turned into a vagabond and having mean people as company, the youth decides to get arrested in order to find a solace against winter. When he finally decides to follow his father advice and get himself a job, he falls under the influence of a policeman, under the false accusation of robbery.

After robbing a bank, a criminal is wrongfully pardoned from prison.